Publications

Production of biofunctionalized MoS2 flakes with rationally modified lysozyme: a biocompatible 2D hybrid material

Marialuisa Siepi, Eden Morales-Narváez, Neus Domingo, Daria Maria Monti, Eugenio Notomista, Arben Merkoçi. 2D Materials, 2017, Vol. 4 (3), pp 035007
Bioapplications of 2D materials embrace demanding features in terms of environmental impact, toxicity and biocompatibility. Here we report on the use of a rationally modified lysozyme to assist the exfoliation of MoS2 bulk crystals suspended in water through ultrasonic exfoliation. The design of the proposed lysozyme derivative...

Graphene-encapsulated materials: Synthesis, applications and trends

Eden Morales-Narváez, Livia Florio, Sergio Antonio Spinola, Arben Merkoçi. Progress in Materials Science, 2017, Vol 86, pp 1-24
Graphene-based materials (GBM) are an exceptional type of materials that offer unprecedented application capabilities to the scientific and technologic community. The encapsulation of different materials such as drugs, nanoparticles, polymers, oxides and cells by GBM is leading to outstanding hybrid materials with unprecedented behaviours...

Straightforward Immunosensing Platform Based on Graphene Oxide-Decorated Nanopaper: A Highly Sensitive and Fast Biosensing Approach

Nopchulee Cheeveewattanagul, Eden Morales-Narváez, Abel-Rahin H. A. Hassan, José Francisco Bergua, Arben Merkoçi. Advanced Functional Materials, 2017, Vol 27 (38), pp 1702741
Immunoassays are nowadays a crucial tool for diagnostics and drug development. However, they often involve time-consuming procedures and need at least two antibodies in charge of the capture and detection processes, respectively. This study reports a nanocomposite based on graphene oxide-coated nanopaper (GONAP) facilitating an advantageous...

Paper strip-embedded graphene quantum dots: a screening device with a smartphone readout

Ruslan Álvarez Diduk, Jahir Orozco, Arben Merkoçi. Scientific Reports, Vol 7, Article number: 976
Simple, inexpensive and rapid sensing systems are very demanded for a myriad of uses. Intrinsic properties of emerging paper-based analytical devices have demonstrated considerable potential to fulfill such demand. This work reports an easy-to-use, low cost, and disposable paper-based sensing device for rapid chemical screening with...

Nanomaterials Based-Platforms for Environmental Monitoring

Flavio Pino, Carmen C. Mayorga-Martínez, Arben Merkoçi. Chapter 7 of the book "Comprehensive Analytical Chemistry", Volume 77, 2017, Pages 207-236
In the last few decades, the development of novel methods for pollutants detection with high accuracy, precision, reproducibility and low detection limits has been a challenge for the scientific community environmental safety. The attractive physicochemical properties of nanostructured materials (metal nanoparticles, QDs, MNPs,...

Magnetic nanoparticle-molecular imprinted polymer: a new impedimetric sensor for tributyltin detection.

Alejandro Zamora, Carmen C. Mayorga-Martínez. Electrochemistry Communications, 2017, Vol 82, pp 6-11
Recently, molecular imprinted polymers (MIPs) were extensively used for separation and identification of specific molecules, replacing expensive and unstable biological receptors. Nonetheless, their application in electrochemical sensors has not been sufficiently explored. Here we report the use of a MIP as a specific receptor in...

Rapid on-chip apoptosis assay on human carcinoma cells based on annexin-V / quantum dot probes

Helena Montón, Mariana Medina-Sánchez, Joan Antoni Soler, Andrzej Chałupniak, Carme Nogués, Arben Merkoçi. Biosensors and Bioelectronics, 2017, Vol 94, pp 408-414
Despite all the efforts made over years to study the cancer expression and the metastasis event, there is not a clear understanding of its origins and effective treatment. Therefore, more specialized and rapid techniques are required for studying cell behaviour under different drug-based treatments. Here we present a quantum dot...

Toward integrated detection and graphene-based removal of contaminants in a lab-on-a-chip platform

Andrzej Chałupniak, Arben Merkoçi. Nano Research, 2017, Vol 10 (7), pp 2296-2310
A novel, miniaturized microfluidic platform was developed for the simultaneous detection and removal of polybrominated diphenyl ethers (PBDEs). The platform consists of a polydimethylsiloxane (PDMS) microfluidic chip for an immunoreaction step, a PDMS chip with an integrated screen-printed electrode (SPCE) for detection, and a PDMS-reduced...

Graphene-Based Biosensors: Going Simple

Eden Morales-Narváez, Luis Baptista-Pires, Alejandro Zamora-Gálvez, and Arben Merkoçi. Advanced Materials, 2017, Vol 29, pp 1604905.
The main properties of graphene derivatives facilitating optical and electrical biosensing platforms are discussed, along with how the integration of graphene derivatives, plastic, and paper can lead to innovative devices in order to simplify biosensing technology and manufacture easy-to-use, yet powerful electrical or optical biosensors....

Paper-based sensors and assays: a success of the engineering design and the convergence of knowledge areas

Adaris M. López-Marzo and Arben Merkoçi. Lab-on-a-chip, 2016, Vol 16, pp 3150-3176
This review shows the recent advances and state of the art in paper-based analytical devices (PADs) through the analysis of their integration with microfluidics and LOC micro- and nanotechnologies, electrochemical/optical detection and electronic devices as the convergence of various knowledge areas. The important role of the paper...