Nanotecnologia i diagnòstic in vitro

Arben Merkoçi. In vitro veritas 2009;10 art.109 (2009)
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Rapid identification and quantification of tumour cells using a novel electrocatalytic method based in gold nanoparticles

Alfredo de la Escosura-Muñiz, Christian Sánchez-Espinel, Belén Díaz-Freitas, África González-Fernández, Marisa Maltez-da Costa, Arben Merkoçi. Analytical Chemistry, 81, p. 10268-10274 (2009)
There is a high demand for simple, rapid, efficient, and user-friendly alternative methods for the detection of cells in general and, in particular, for the detection of cancer cells. A biosensor able to detect cells would be an all-in-one dream device for such applications. The successful integration of nanoparticles into cell detection...

The Usage of Bismuth Film Electrode as Transducer in Glucose Biosensing

Ülkü Anık, Suna Timur, Meliha Çubukçu, Arben Merkoçi. Microchim Acta 160, p. 269 (2008)
A second generation glucose biosensor was developed by using neutral red (NR) as a mediator and a bismuth film electrode (BiFE) as a transducer along with immobilized glucose oxidase. The linear range was between 0.2 and 2.5 mM, and a correlation coefficient of 0.999 was obtained with this electrode. The standard deviation (at...

A Carbon Nanotube PVC Based Matrix Modified with Glutaraldehyde Suitable for Biosensor Applications

Briza Pérez-López, Joan Sola, Salvador Alegret, Arben Merkoçi. Electroanalysis 20, (6), p. 603 (2008)
Carbon nanotubes (CNTs) are offering a great promise for developing electrochemical sensors. Distinctive properties of CNTs such as a high surface area, ability to accumulate analyte, minimization of surface fouling and electrocatalytic activity are very attractive for electrochemical sensing. The electrochemical study of a glassy...

Enhanced host-guest electrochemical recognition of dopamine using cyclodextrin in the presence of carbon nanotubes

Georgina Alarcon Angeles, Briza Pérez-López, Manuel Eduardo Palomar-Pardave, Maria Teresa Ramírez-Silva, Salvador Alegret, Arben Merkoçi. Carbon 46, p. 898 (2008)
A novel application of multiwall carbon nanotubes (MWCNT) for biosensor use is presented. β-Cyclodextrin (β-CD) as molecular receptor and MWCNT as enhancer of electron transfer are integrated in a dopamine (DA) electrochemical sensor system. The proposed molecular host–guest recognition based sensor has a high electrochemical...

Application of carbon nanotubes in analytical chemistry

Briza Pérez-López, Arben Merkoçi. Chapter at “Chemistry of Carbon Nanotubes” (V.A. Basiuk and E.V. Basiuk, Eds.). American Scientific Publishers (2008)

Silver, gold and the corresponding core shell nanoparticles for sensing applications

Fraser Douglas, Ramon Yanez, Josep Ros, Sergio Marín, Alfredo de la Escosura-Múñiz, Salvador Alegret, Arben Merkoçi. Journal of Nanoparticle Research, 10, p. 97 (2008)
Simple strategies for producing silver and gold nanoparticles (AgNP and AuNP) along with the corresponding core shell nanoparticles (Au–Ag and Ag–Au) by reduction of the metal salts AgBF4 and HAuCl4 by NaBH4 in water will be presented. The morphologies of the obtained nanoparticles are determined by the order of addition of reactants....

Electrochemical analysis with nanoparticle based biosystems

Alfredo de la Escosura-Muñiz, Adriano Ambrosi, Arben Merkoçi. Trends in Analytical Chemistry, 27 (7), p. 568 (2008)
We give a general overview on the application of electrochemical analysis to biosensing using nanoparticles (NPs). We describe several examples of applications of voltammetric, potentiometric, conductometric, impedimetric and scanning electrochemical microscope-based methods in NP characterization, detection and quantification. We...

Sensitive and stable monitoring of lead and cadmium in seawater using screen-printed electrode and electrochemical stripping analysis

Raquel Güell, Gemma Aragay, Clàudia Fontàs, Enriqueta Anticó, Arben Merkoçi. Anal. Chim. Acta 627, p. 219 (2008)
Sensitive and stable monitoring of heavy metals in seawater using screen-printed electrodes (SPE) is presented. The analytical performance of SPE coupled with square wave anodic stripping voltammetry (SWASV) for the simultaneous determination of Pb and Cd in seawater samples, in the low μg L−1 range, is evaluated. The stripping...

Quantum dots (QDs) as tracers for DNA electrochemical sensing systems

Arben Merkoçi, Salvador Alegret. Nanotechnology in Biology and Medicine. Methods, Devices and Applications, Chapter 26. p. 26-1( 2007)