Publications

Daniel Quesada-Gonzalez's Publications

Quantum dots for biosensing: Classification and applications

Daniel Quesada-Gonzalez, Arben Merkoçi, . Biosensors and Bioelectronics
Quantum dots (QDs) are the smallest nanomaterials (2–10 nm), with unique optical and electronic properties. Thanks to these properties, QDs have been standing during the last years as signal tags for different applications, including bioimaging, fluorescent biosensors and electrochemical assays. In this review, we explore...

High resolution portable platform for pH sensing via colorimetric fluorescence of carbon dots

Gianluca Minervini, Annamaria Panniello, Daniel Quesada-González, Gabriel Maroli, Elisabetta Fanizza, Marinella Striccoli, Ruslan Álvarez-Diduk, Maria Lucia Curri, Arben Merkoçi. Chemical Engineering Journal
Portable sensing platforms based on nanoparticles are becoming increasingly significant across diverse fields, as they enable real-time measurements in various environments without complex lab protocols. Carbon dots (CDs), known for low toxicity and intense fluorescence, can exhibit pH-dependent optical emission, generally related...

Lateral flow immunoassay for simultaneous detection of C. difficile, MRSA, and K. pneumoniae

Ana Rubio-Monterde, Lourdes Rivas, Marc Gallegos, Daniel Quesada-González, Arben Merkoçi. Microchimica Acta
Mainly performed within a rapid diagnostic tests company, a lateral flow (LF) system using gold nanoparticles (AuNPs) as transducers is presented able to detect three bacteria of interest, of relevance for antimicrobial resistance (AMR): Clostridioides difficile, methicillin-resistant Staphylococcus aureus (MRSA), and Klebsiella...

Toward Integrated Molecular Lateral Flow Diagnostic Tests Using Advanced Micro- and Nanotechnology

Ana Rubio-Monterde, Daniel Quesada-González, Arben Merkoçi. Analytical Chemistry
Since the COVID-19 pandemic, some of the routine methods for clinical diagnosis of infectious diseases have become closer to the general population and terms like “PCR” (polymerase chain reaction) and “antigen rapid diagnostic test” (RDT) are not restricted only to the scientific community but now also commonly appear in...

Integrating gold nanoclusters, folic acid and reduced graphene oxide for nanosensing of glutathione based on “turn-off” fluorescence

Xin Yi Wong, Daniel Quesada-González, Sivakumar Manickam, Siu Yee New, Kasturi Muthoosamy, Arben Merkoçi. Scientific Reports
Glutathione (GSH) is a useful biomarker in the development, diagnosis and treatment of cancer. However, most of the reported GSH biosensors are expensive, time-consuming and often require complex sample treatment, which limit its biological applications. Herein, a nanobiosensor for the detection of GSH using folic acid-functionalized...

Tutorial: design and fabrication of nanoparticle-based lateral-flow immunoassays

Claudio Parolo, Amadeo Sena-Torralba, José Francisco Bergua, Enric Calucho, Celia Fuentes-Chust, Liming Hu, Lourdes Rivas, Ruslan Álvarez-Diduk, Emily P. Nguyen, Stefano Cinti, Daniel Quesada-González & Arben Merkoçi. Nature Protocols
Lateral-flow assays (LFAs) are quick, simple and cheap assays to analyze various samples at the point of care or in the field, making them one of the most widespread biosensors currently available. They have been successfully employed for the detection of a myriad of different targets (ranging from atoms up to whole cells) in all...

Iridium oxide (IV) nanoparticle-based lateral flow immunoassay

Daniel Quesada-González, Amadeo Sena-Torralba, Wiyogo Prio Wicaksono, Alfredo de la Escosura-Muñiz, Tribidasari A. Ivandini, Arben Merkoçi. Biosensors and Bioelectronics, 2019, Vol 132, pp 132-135,
Lateral flow biosensors are paper-based devices that allow the detection of different types of analytes with quickness, robustness, and selectivity, without leaving behind paper sensors benefits as low-cost, recyclability and sustainability. Nanomaterials have been widely reported in lateral flow biosensors, offering new sensing...

Signal enhancement on gold nanoparticle-based lateral flow tests using cellulose nanofibers

Daniel Quesada-González, Christina Stefani, Israel González, Alfredo de la Escosura-Muñiz, Neus Domingo, Pere Mutjé, Arben Merkoçi. Biosensors and Bioelectronics, 2019, Vol 141, pp 111407
Lateral flow paper-based biosensors merge as powerful tools in point-of-care diagnostics since they are cheap, portable, robust, selective, fast and easy to use. However, the sensitivity of this type of biosensors is not always as high as required, often not permitting a clear quantification. To improve the colorimetric response...

Nanotecnología en los Biosensores de Papel

Daniel Quesada-González, Arben Merkoçi. Sociedad Española de Química Analítica, nº63
Click on the picture, and then, link to the journal: here

Iridium oxide (IV) nanoparticle-based electrocatalytic detection of PBDE

Damiel Quesada-González, Alessandra Baiocco, Andrea A. Martos, Alfredo de la Escosura-Muñiz, Arben Merkoçi. Biosensors and Bioelectronics, 2019, Vol 127, pp 150-154,
Polybrominated diphenyl ethers (PBDEs) are a type of flame retardants which are currently banned in EU and USA due their hazardousness for humans and mammals. However, these compounds were highly used during more than 30 years and still persist in the environment since they are resistant to degradation. Herein we present a biosensor for...