Aminopyrazole based ligand induces gold nanoparticle formation and remains available for heavy metals sensing. A simple ‘mix and detect’ approach.

Gemma Aragay, Josefina Pons, Josep Ros, Arben Merkoçi. Langmuir 26, p. 10165-10170 (2010)

A novel way to synthesize gold nanoparticles based on the use of N-alkylaminopyrazole is shown. This ligand has a triple functionality: induces AuNPs formation, stabilizes the formed nanoparticles, and even remains available for an external coordination with heavy metal ions. The availability of N-alkylaminopyrazole ligands onto the AuNPs surface is studied using UV-vis and NMR techniques. The mechanism of formation of AuNPs along with the synthesis optimization and characterization are studied using voltammetry and UV-vis, and the results are discussed in detail. The application of N-alkylaminopyrazole-derived gold nanoparticles in the heavy metal ions sensing is also tested showing a high sensitivity for mercury detection at low concentration level. The functionalization of metal nanoparticles with these receptors followed by heavy metal ions detection represents a simple «mix and detect» approach with interest for several other sensing applications.

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