Nanocellulose in Sensing and Biosiensing

Hamed Golmohammadi, Eden Morales-Narváez, Tina Naghdi, Arben Merkoçi. Chemistry of Materials, Available online 9 June 2017, doi: 10.1021/acs.chemmater.7b01170
Because of its multifunctional character, nanocellulose (NC) is one of the most interesting nature-based nanomaterials and is attracting attention in a myriad of fields such as biomaterials, engineering, biomedicine, opto/electronic devices, nanocomposites, textiles, cosmetics and food products. Moreover, NC offers a plethora of...

Bioluminescent nanopaper for rapid screening of toxic substances

Jie Liu, Eden Morales-Narváez, Jahir Orozco, Teresa Vincent, Guohua Zhong, Arben Merkoçi. NanoResearch, Available online 2 August 2017, doi: 10.1007/s12274-017-1610-7
Environmental pollution is threatening human health and ecosystems as a result of modern agricultural techniques and industrial progress. A simple nanopaper-based platform coupled with luminescent bacteria Aliivibrio fischeri (A. fischeri) as a bio-indicator is presented here, for rapid and sensitive evaluation of contaminant toxicity....

Production of biofunctionalized MoS2 flakes with rationally modified lysozyme: a biocompatible 2D hybrid material

Marialuisa Siepi, Eden Morales-Narváez, Neus Domingo, Daria Maria Monti, Eugenio Notomista, Arben Merkoçi. 2D Materials, Available Online 2 July 2017, doi: 10.1088/2053-1583/aa7966
Bioapplications of 2D materials embrace demanding features in terms of environmental impact, toxicity and biocompatibility. Here we report on the use of a rationally modified lysozyme to assist the exfoliation of MoS2 bulk crystals suspended in water through ultrasonic exfoliation. The design of the proposed lysozyme derivative...

Graphene-encapsulated materials: Synthesis, applications and trends

Eden Morales-Narváez, Livia Florio, Sergio Antonio Spinola, Arben Merkoçi. Progress in Materials Science, Available online May 2017, 10.1016/j.pmatsci.2017.01.001
Graphene-based materials (GBM) are an exceptional type of materials that offer unprecedented application capabilities to the scientific and technologic community. The encapsulation of different materials such as drugs, nanoparticles, polymers, oxides and cells by GBM is leading to outstanding hybrid materials with unprecedented behaviours...

Straightforward Immunosensing Platform Based on Graphene Oxide-Decorated Nanopaper: A Highly Sensitive and Fast Biosensing Approach

Nopchulee Cheeveewattanagul, Eden Morales-Narváez, Abel-Rahin H. A. Hassan, José Francisco Bergua, Arben Merkoçi. Advanced Functional Materials, Available online 11 August 2017, doi: 10.1002/adfm.201702741
Immunoassays are nowadays a crucial tool for diagnostics and drug development. However, they often involve time-consuming procedures and need at least two antibodies in charge of the capture and detection processes, respectively. This study reports a nanocomposite based on graphene oxide-coated nanopaper (GONAP) facilitating an advantageous...

Paper strip-embedded graphene quantum dots: a screening device with a smartphone readout

Ruslan Álvarez Diduk, Jahir Orozco, Arben Merkoçi. Scientific Reports, Available online 20 April 2017, doi: 10.1038/s41598-017-01134-3
Simple, inexpensive and rapid sensing systems are very demanded for a myriad of uses. Intrinsic properties of emerging paper-based analytical devices have demonstrated considerable potential to fulfill such demand. This work reports an easy-to-use, low cost, and disposable paper-based sensing device for rapid chemical screening with...

Nanomaterials Based-Platforms for Environmental Monitoring

Flavio Pino, Carmen C. Mayorga-Martínez, Arben Merkoçi. Chapter 7 of the book "Comprehensive Analytical Chemistry", Volume 77, 2017, Pages 207-236
In the last few decades, the development of novel methods for pollutants detection with high accuracy, precision, reproducibility and low detection limits has been a challenge for the scientific community environmental safety. The attractive physicochemical properties of nanostructured materials (metal nanoparticles, QDs, MNPs,...

Magnetic nanoparticle-molecular imprinted polymer: a new impedimetric sensor for tributyltin detection.

Alejandro Zamora, Carmen C. Mayorga-Martínez. Electrochemistry Communications, Available online September 2017, doi: 10.1002/adma.201604905
Recently, molecular imprinted polymers (MIPs) were extensively used for separation and identification of specific molecules, replacing expensive and unstable biological receptors. Nonetheless, their application in electrochemical sensors has not been sufficiently explored. Here we report the use of a MIP as a specific receptor in...

Rapid on-chip apoptosis assay on human carcinoma cells based on annexin-V / quantum dot probes

Helena Montón, Mariana Medina-Sánchez, Joan Antoni Soler, Andrzej Chałupniak, Carme Nogués, Arben Merkoçi. Biosensors and Bioelectronics, Available online 18 March 2017, http://dx.doi.org/10.1016/j.bios.2017.03.034
Despite all the efforts made over years to study the cancer expression and the metastasis event, there is not a clear understanding of its origins and effective treatment. Therefore, more specialized and rapid techniques are required for studying cell behaviour under different drug-based treatments. Here we present a quantum dot...

Toward integrated detection and graphene-based removal of contaminants in a lab-on-a-chip platform

Andrzej Chałupniak, Arben Merkoçi. Nano Research (2017), doi:10.1007/s12274-016-1420-3
A novel, miniaturized microfluidic platform was developed for the simultaneous detection and removal of polybrominated diphenyl ethers (PBDEs). The platform consists of a polydimethylsiloxane (PDMS) microfluidic chip for an immunoreaction step, a PDMS chip with an integrated screen-printed electrode (SPCE) for detection, and a PDMS-reduced...