Development of a Nanodiagnostic platform for monitoring of Cancer cell secreted proteins (NACANCELL)

Reference: PCIN-2016-066

Funded by: MINECO (Spanish Government)

Period: 01/11/2016 – 30/10/2019

logo MINECO 2017

Partners:

Fundació Institut Català de Nanociència i Nanotecnologia, University of Bordeaux-Inserm, Institut de Recerca Pediàtrica – Hospital Sant Joan de Déu, Skannex.

 

Summary:

NACANCELL aims at developing an innovative paper-based sensor to quantify parathyroid hormone-like hormone (PTHLH), a protein that exerts critical roles in cancer. The project will focus on neuroblastoma, a childhood cancer, but will impact the field of clinical oncology and cancer research as well through its future easy application to other biomarkers. The main objective will be to generate an innovative device to monitor PTHLH production in in vitro cancer models as well as in plasma samples of cancer patients. This will allow for a fast, easy and cost effective monitoring of cancer cells activity for research purposes, but, more importantly, it will provide a precise evaluation of tumor evolution and response to treatments in liquid biopsies of cancer patients.